ANASTROL-1 is an post cycle steroid, its active substance is Anastrozole and is made by Global Anabolic.
ANASTROL-1 is a potent and selective non-steroidal aromatase inhibitor indicated for the treatment of advanced breast cancer in post-menopausal women with disease progression following tamoxifen therapy. Many breast cancers have estrogen receptors and growth of these tumors can be stimulated by estrogens. In post-menopausal women, the principal source of circulating estrogen (primarily estradiol) is conversion of adrenally-generated androstenedione to estrone by aromatase in peripheral tissues, such as adipose tissue, with further conversion of estrone to estradiol. Many breast cancers also contain aromatase, the importance of tumor-generated estrogens is uncertain. Treatment of breast cancer has included efforts to decrease estrogen levels by ovariectomy premenopausally and by use of anti-estrogens and progestational agents both pre- and post-menopausally, and these interventions lead to decreased tumor mass or delayed progression of tumor growth in some women. ANASTROL-1 is a potent and selective non-steroidal aromatase inhibitor. It significantly lowers serum estradiol concentrations and has no detectable effect on formation of adrenal corticosteroids or aldosterone.
ANASTROL-1 is the first in a new class of third-generation selective oral aromatase inhibitors. It acts by blocking the enzyme aromatase, subsequently blocking the production of estrogen. Since many forms of breast cancer cells are stimulated by estrogen, it is hoped that by reducing amounts of estrogen in the body the progression of such a disease can be halted. This is the basic premise behind Nolvadex, except this drug blocks the action and not production of estrogen. The effects of ANASTROL-1 can be quite dramatic to say the least. A daily dose of one tablet can produce estrogen suppression greater than 80 % in treated patients. With the powerful effect this drug has on hormone levels, it is only to be used (clinically) by post-menopausal women whose disease has progressed following treatment with Nolvadex (tamoxifen citrate). Side effects like hot flushes and hair thinning can be present, and would no doubt be much more.

For the steroid using male athlete, ANASTROL-1 shows great potential. Up to this point, drugs like Nolvadex and Proviron have been our weapons against excess estrogen. These drugs, especially in combination, do prove quite effective. But ANASTROL-1 appears able to do the job much more efficiently, and with less hassle. A single tablet daily, the same dose use clinically, seems to be all one needs for an exceptional effect (some even report excellent results with only 0.25 mg daily). When used with strong, readily aromatizing androgens such as Dianabol or testosterone, gynecomastia and water retention can be effectively blocked. In combination with Propecia (finasteride), we have a great advance. With the one drug halting estrogen conversion and the other blocking 5-alpha reduction , related side effects can be effectively minimized. Here the strong androgen testosterone could theoretically provide incredible muscular growth, while at the same time being as tolerable as nandrolone. Additionally the quality of the muscle should be greater, the athlete appearing harder and much more defined without holding excess water.
In the majority of users, 0.5 mg per day should be enough to prevent any estrogen related side effects related to anabolic steroid use. Even when doses were increased to 1 mg per day there was no change in the amount of estrogen that was able to be reduced as compared to doses of 0.5 mg per day. This would seem to indicate that raising your dosage will show no further results if estrogenic side effects continue to be a problem at a dosage of 0.5 mg. If symptoms persist the user may have to try a more potent compound such as femara.
Having said all of this however, most users will be able to reduce any water retention that they may have, or other estrogen related side effects, with dose less than 0.5 mg per day. Anecdotally users have reported that doses in the range of 0.25 mg per day or 0.5 mg every other day are enough to acheive this result. It is possible to administer ANASTROL-1 every other day due to it's active life of 48 hours.
For users using ANASTROL-1 during their post cycle therapy the same dosages should apply. There is no need to increase or decrease dosages. It can be run throughout the post cycle period with no ill effects.
Blood levels of the compound should stabilize and reach their peak at about 7 - 10 days after first administering the drug. Therefore it is unlikely that a user would need to frontload with ANASTROL-1 or begin taking it before they start administering the anabolics that they plan on taking.

SIDE EFFECTS:
ANASTROL-1 is seemingly very mild on blood lipids (cholesterol) and has not been shown to affect them adversely. However it should be noted that in theory if one was to consistently suppress your natural estrogen levels for a long period of time, this would negatively impact your health (including your cholesterol). Despite this there is no scientific evidence that ANASTROL-1 can be dangerous for healthy individuals to use, even for extended periods of time.
It would seem then that ANASTROL-1 has little in the way of negative side effects associated with it's use. It is by far one of the safest compounds that an athlete can use.